benchmarKIN - Evaluation of methods for kinase activity inference

benchmarKIN is a package for evaluation of kinase activity inference tools. It provides two complementary benchmarking approaches for evaluation: The perturbation-based benchmark approach and the tumor-based benchmark approach.

benchmarKIN's workflow — benchmarKIN contains two complementary approaches for kinase activity inference

Check out the perturbation-based or tumor-based benchmark sections for further information, of how test your own kinase activity inference method.

If you have any question or problem do not hesitate to open an issue.

Citation

Mueller-Dott, Sophia, Eric J. Jaehnig, Khoi Pham Munchic, Wen Jiang, Tomer M. Yaron-Barir, Sara R. Savage, Martin Garrido-Rodriguez, et al. 2024. “Comprehensive Evaluation of Phosphoproteomic-Based Kinase Activity Inference.” bioRxiv. https://doi.org/10.1101/2024.06.27.601117.